Combined influence of high fluoride and high iodine in drinking water on prevalence of dental fluorosis in school-age children in the countryside of Tianjin
王睿 ； 300011,天津市疾病预防控制中心环境与健康所 ； 王睿 ； 曾强 ； 侯常春 ； 崔维琪 ； 张磊 ； 冯宝佳 ； 赵亮 ； 崔玉山 ； 刘洪亮
中华地方病学杂志 ； 2014年 06期 (2014 / 12 / 25) ， P630 - 632
https://www.airitilibrary.com/Publicati ... z201406010
Wang R, Zeng Q, Hou C, et al. - "Combined influence of high fluoride and high iodine in drinking water on prevalence of dental fluorosis in school-age children in the countryside of Tianjin" Chinese Journal of Endemiology 33(6):630-632 (2014)
https://www.cabdirect.org/globalhealth/ ... 0153067288
https://www.researchgate.net/publicatio ... of_Tianjin
目的 观察高氟高碘饮水对天津市农村学龄儿童氟斑牙患病的影响.方法 依据天津市农村饮用水中氟含量和碘含量的筛查结果,在天津市选择静海县和武清区的3个乡镇分别作为高氟高碘组、高氟适碘组及适氟适碘(对照)组,以8～10岁农村儿童作为调查对象,采集晨尿,氟离子选择电极法(WS/T 89-1996)检测尿氟,砷铈催化分光光度法(WS/T 107-2006)测定尿碘,采用Dean法检查氟斑牙患病情况.应用SPSS 11.5软件对数据进行x2检验、Logistic分析.结果 高氟高碘组、高氟适碘组及对照组儿童尿氟中位数分别为2.48、2.70、1.59 mg/L,尿碘中位数分别为721.7、788.3、293.5 μg/L,组间比较,差异均有统计学意义(x2值分别为35.10、17.01,P均＜0.05).氟斑牙检出率由高至低依次为高氟适碘组(85.3％,29/34)、高氟高碘组(66.7％,14/21)、对照组(48.8％,21/43),组间比较差异有统计学意义(×2=15.39,P＜0.05).Logistic分析表明,高水氟是氟斑牙的患病危险因素[比值比(OR)为7.273,95％可信区间(CI)为1.676 ～ 31.562,x2=7.020,P＜0.05].结论 饮水高氟及高氟高碘慢性暴露对氟斑牙检出率产生一定的影响.
Objective To investigate the joint effects of excessive fluoride and iodine in drinking water on school-age children's dental fluorosis in the countryside of Tianjin.Methods Based on the screening results of fluorine and iodine contents in drinking water in rural areas of Tianjin,three towns in Jinghai County and Wuqing District of Tianjin were selected as high fluoride and high iodine group,high fluoride and suitable iodine group,suitable fluoride and suitable iodine(control) group.Children aged 8-10 were selected as survey subjects.Morning urine was collected and dental fluorosis was examined.The concentration of urinary iodine was determined using arsenic cerium catalytic spectrophotometry(WS/T 107-2006),and urinary fluoride was detected using fluoride ion selective electrode method (WS/T 89-1996).Dean method was used to check the prevalence of dental fluorosis.Results The urinary iodine median was 721.7,788.3,293.5 μg/L,respectively,and urinary fluorosis median was 2.48,2.70,1.59 mg/L,respectively.Urinary iodine and fluorosis were the highest in high fluoride and high iodine group,followed by high fluoride and suitable iodine group and control group(x2 =35.10,17.01,all P ＜ 0.05).There was a significant difference of prevalence of dental fluorosis among the three groups(x2 =15.39,P＜ 0.05).The prevalence of dental fluorosis was the highest in high fluoride and suitable iodine group(85.3％,29/34),followed by high fluoride and high iodine group(66.7％,14/21) and control group(48.8％,21/43).Multiple Logistic regression analysis showed that the prevalence of dental fluorosis was adversely associated with fluorine concentration in drinking water[OR =7.273,95％ confidence limits(CI):1.676 ～ 31.562,x2 =7.020,P ＜ 0.05].Conclusion Drinking water with high fluoride and exposure of high fluoride combined with high iodine has a definite impact on children's dental fluorosis.
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