Cao Q, Wang J, Hao Y, Zhao F, Fu R, Yu Y, Wang J, Niu R, Bian S, Sun Z - "Exercise Ameliorates Fluoride-induced Anxiety- and Depression-like Behavior in Mice: Role of GABA" Biol Trace Elem Res (2021) doi: 10.1007/s12011-021-02678-2
https://pubmed.ncbi.nlm.nih.gov/33825162/
Chai L, Cao Q, Liu K, Zhu R, Li H, Yu Y, Wang J, Niu R, Zhang D, Yang B, Ommati MM, Sun Z - "Exercise Alleviates Fluoride-Induced Learning and Memory Impairment in Mice: Role of miR-206-3p and PREG" Biol Trace Elem Res. 2024 Jan 20. doi: 10.1007/s12011-024-04068-w
https://link.springer.com/article/10.10 ... 24-04068-w
Fu R, Niu R, Zhao F, Wang J, Cao Q, Yu Y, Liu C, Zhang D, Sun Z - "Exercise alleviated intestinal damage and microbial disturbances in mice exposed to fluoride" Chemosphere 132658 (2021)
https://www.sciencedirect.com/science/a ... 3521031301
Li R, Gong Z, Yu Y, Niu R, Bian S, Sun Z - "Alleviative Effects of Exercise on Bone Remodeling in Fluorosis Mice" Biol Trace Elem Res 200(3):1248-1261 (2021) doi: 10.1007/s12011-021-02741-y
https://link.springer.com/article/10.10 ... 21-02741-y
Liu K, Chai L, Zhao T, Zhang S, Wang J, Yu Y, Niu R, Sun Z - "Effects of Treadmill Exercise on Liver Apoptosis in Fluoride-Exposed Mice" Biol Trace Elem Res 201(12):5734-5746 (2023) doi: 10.1007/s12011-023-03619-x.
https://link.springer.com/article/10.10 ... 23-03619-x
Mahmood M, Azevedo LB, Maguire A, Buzalaf M, Zohoori FV - "Pharmacokinetics of fluoride in human adults: The effect of exercise" Chemosphere 262:127796 (2020)
https://pubmed.ncbi.nlm.nih.gov/32755695/
Zhang Zigui, Xu Xiaohong, Shen Xiuying, et al. - "Effects of chronic fluorosis on learning and memory behavior and exercise tolerance in mice" China Public Health 15(3): 186-187 (1999) doi: 10.3321/j.issn:1001-0580.1999.03.006
Thyroid
There are hundreds of studies documenting the effects of exercise on thyroid hormone metabolism. Listed below are a few from the last few decades with a focus on deiodinases.
Bocco BM, Louzada RA, Silvestre DH, Santos MC, Anne-Palmer E, Rangel IF, Abdalla S, Ferreira AC, Ribeiro MO, Gereben B, Carvalho DP, Bianco AC, Werneck-de-Castro JP - "Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-γ coactivator-1α expression in skeletal muscle" J Physiol 594(18):5255-69 (2016). doi: 10.1113/JP272440
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023700/
Fortunato RS, Ignácio DL, Padron AS, Peçanha R, Marassi MP, Rosenthal D, Werneck-de-Castro JP, Carvalho DP - "The effect of acute exercise session on thyroid hormone economy in rats" J Endocrinol 198(2):347-53 (2008). doi: 10.1677/JOE-08-0174
https://joe.bioscientifica.com/view/jou ... /2/347.xml
Gao Y, Zhao L, Son JS, Liu X, Chen Y, Deavila JM, Zhu MJ, Murdoch GK, Du M - "Maternal Exercise Before and During Pregnancy Facilitates Embryonic Myogenesis by Enhancing Thyroid Hormone Signaling" Thyroid 32(5):581-593 (2022) doi: 10.1089/thy.2021.0639
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145266/
Ignacio DL, da S Silvestre DH, Cavalcanti-de-Albuquerque JP, Louzada RA, Carvalho DP, Werneck-de-Castro JP - "Thyroid hormone and estrogen regulate exercise-induced growth hormone release" PLoS One 10(4):e0122556 (2015). doi: 10.1371/journal.pone.0122556
https://pubmed.ncbi.nlm.nih.gov/25874614/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395113/
Katzeff HL, Bovbjerg D, Mark DA - "Exercise regulation of triiodothyronine metabolism" Am J Physiol 255(6 Pt 1):E824-8 (1988). doi: 10.1152/ajpendo.1988.255.6.E824
https://journals.physiology.org/doi/abs ... 255.6.E824
Liu Q, Li H, He W, Zhao Q, Huang C, Wang Q, Zheng Z, Zhang X, Shi X, Li X - "Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones" Front Endocrinol (Lausanne) 13:1075986 (2022) doi: 10.3389/fendo.2022.1075986.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807753/
Marschner RA, Banda P, Wajner SM, Markoski MM, Schaun M, Lehnen AM - "Short-term exercise training improves cardiac function associated to a better antioxidant response and lower type 3 iodothyronine deiodinase activity after myocardial infarction" PLoS One 14(9):e0222334 (2019). doi: 10.1371/journal.pone.0222334
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742396/
Neto RA, de Souza Dos Santos MC, Rangel IF, Ribeiro MB, Cavalcanti-de-Albuquerque JP, Ferreira AC, Cameron LC, Carvalho DP, Werneck de Castro JP - "Decreased serum T3 after an exercise session is independent of glucocorticoid peak" Horm Metab Res 45(12):893-9 (2013) doi: 10.1055/s-0033-1351279
https://www.thieme-connect.com/products ... 33-1351279
Rosołowska-Huszcz D - "The effect of exercise training intensity on thyroid activity at rest" J Physiol Pharmacol 49(3):457-66 (1998)
https://pubmed.ncbi.nlm.nih.gov/9789797/
Sullo A, Brizzi G, Maffulli N - "Deiodinating activity in the brown adipose tissue of rats following short cold exposure after strenuous exercise" Physiol Behav 80(2-3):399-403 (2003). doi: 10.1016/j.physbeh.2003.09.005
https://www.sciencedirect.com/science/a ... 8403002968
Uribe RM, Jaimes-Hoy L, Ramírez-Martínez C, García-Vázquez A, Romero F, Cisneros M, Cote-Vélez A, Charli JL, Joseph-Bravo P - "Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats" Endocrinology 155(5):2020-30 (2014). doi: 10.1210/en.2013-1724
https://academic.oup.com/endo/article/1 ... 20/2423689
Werneck FZ, Coelho EF, Almas SP, Garcia MMDN, Bonfante HLM, Lima JRP, Vigário PDS, Mainenti MRM, Teixeira PFDS, Vaisman M - "Exercise training improves quality of life in women with subclinical hypothyroidism: a randomized clinical trial" Arch Endocrinol Metab 62(5):530-536 (2018). doi: 10.20945/2359-3997000000073
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118651/