2023: Fluoride in drinking water as a risk factor for the development of subclinical hypothyroidism

All adverse health effects of fluoride are related to thyroid hormone metabolism.
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2023: Fluoride in drinking water as a risk factor for the development of subclinical hypothyroidism

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Ecaterina Gorceag E, Marian-Pavlenco A - "Fluoride in Drinking Water as a Risk Factor for the Development of Subclinical Hypothyroidism" The 8th Congress on Urology, Dialysis, and Kidney Transplant from the Republic of Moldova with International Participation: "New Horizons in Urology"
The National Section from the Republic of Moldova of the Balkan Medical Union and the Moldovan Society of Urologists June 7-9, 2023
Chisinau, Republic of Moldova Abstract Only
https://ibn.idsi.md/sites/default/files ... e_book.pdf

ABSTRACT

Introduction: It has been scientifically proven that there is an association between subclinical hypothyroidism (SCH) during pregnancy and hypertension in pregnancy, preterm birth, and impaired cognitive development of children. There are data on the consumption of fluoridated drinking water and the development of subclinical hypothyroidism during pregnancy.

Material and Methods: Fluoride in drinking water increases the risk of subclinical hypothyroidism. The study conducted in Canada divided pregnant women into euthyroid (n=1301), with subclinical hypothyroidism (n=100), and primary hypothyroid (n=107). Fluoride levels in consumed water and in some urine samples were measured, and the impact of fluoridated water consumption on pregnant women in the described groups was estimated. In the Republic of Moldova, data on the fluoride content, taken from the registers of the Public Health Centers for the period 2010-2017, were analyzed. In the Republic of Moldova, there are districts where the fluoride concentration essentially exceeds the normative limit.

Results: Among women with normal antiTPO levels in Canada, the risk of primary hypothyroidism increased with increasing fluoride-containing water intake (OR water fluoride concentration: 2.85; 95% CI: 1.25, 6.50). At the same time, the data analysis of 150 pregnant women from different regions of the Republic of Moldova demonstrated the higher incidence of subclinical hypothyroidism in pregnant women living in districts where the fluoride content in the water is high (Ceadîr-Lunga, Ștefan-Vodă).

Conclusions: Additional research is needed for the regions of the Republic of Moldova to establish the rapport between fluoride in drinking water and subclinical hypothyroidism in pregnant women.

COMMENT (Wendy): Unfortunately, this abstract spends more time on the faulty Canadian York/MIREC study (Hall et al., 2023) than actual findings in Moldova. Hopefully, there will be a paper published soon. Note: In the Canadian study, the hypothyroid women consumed 470 μg/day of iodine; the ones with subclinical hypothyroidism 458.0 μg/day. WHO recommendation is 250 μg/day. SEE: https://poisonfluoride.brouhahagroup.co ... =97&t=5022
  • NOTE: Fluoride water content:
    Ceadâr-Lunga: 1.13 ppm
    Ștefan Vodă: 1.44 ppm

    In: Bivol N, Ciobanu E - "Hygienic Analysis of Fluoride Content in Drinking Water in Some Settlements of the Republic of Moldova" Arta Medica (2020) 4(77):17-19 (2020)
    https://zenodo.org/records/4173240
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