Yadykina TK, Bugaeva MS, Kochergina TV, Mikhailova NN - "Clinical and experimental studies of the effect of chronic fluoride intoxication on the hormonal status of the body and morphological changes in the thyroid gland" Russian Journal of Occupational Health and Industrial Ecology 61(3):173-180 (2021)
Conclusions. Clinical studies of individuals with chronic fluoride intoxication and concomitant endocrinopathy revealed a significant increase in the number of workers with abdominal obesity, musculoskeletal disorders, mineral metabolism disorders. Also, with deforming osteoarthritis of the joints, osteoalgia against the background of thyroid insufficiency. Experimental data confirm this. The fluorine accumulation in the body causes multidirectional disorders of the hormonal mechanisms of regulation of metabolic processes, alternation of hypo- and hyperfunction changes in the thyroid gland associated with fluoride duration intoxication.
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