Vitamin D - Solutions

A forum investigating the similarities between COVID-19 and fluoride poisoning, thyroid dysfunction and Gq/11 pathways.

Vitamin D - Solutions

Postby admin » Mon May 25, 2020 10:25 am

Vitamin D
© 2020 PFPC

COVID-19

Mitchell F - "Vitamin-D and COVID-19: do deficient risk a poorer outcome?" Lancet Diabetes Endocrinol S2213-8587(20)30183-2 (2020) doi: 10.1016/S2213-8587(20)30183-2. Epub ahead of print. PMID: 32445630.

Martín Giménez VM, Inserra F, Tajer CD, Mariani J, Ferder L, Reiter RJ, Manucha W - "Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment" Life Sci 254:117808. (2020) doi: 10.1016/j.lfs.2020.117808. Epub ahead of print. PMID: 32422305; PMCID: PMC7227533
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227533/

Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP - "Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths" Nutrients 12(4):988 (2020) doi: 10.3390/nu12040988. PMID: 32252338; PMCID: PMC7231123.
https://pubmed.ncbi.nlm.nih.gov/32252338/

Fluoride

Bondu JD, Seshadri MS, Selvakumar R, Fleming JJ - "Effects of Fluoride on Bone in an Animal Model of Vitamin D Deficiency" Indian J Clin Biochem 34(1):60-67. doi: 10.1007/s12291-017-0709-7 (2019) Epub 2017 Nov 13. PMID: 30728674; PMCID: PMC6346609
https://pubmed.ncbi.nlm.nih.gov/30728674

Khandare AL, Validandi V, Gourineni SR, Gopalan V, Nagalla B - "Dose-dependent effect of fluoride on clinical and subclinical indices of fluorosis in school going children and its mitigation by supply of safe drinking water for 5 years: An Indian study" Environ Monit Assess. 190(3):110 (2018)
https://pubmed.ncbi.nlm.nih.gov/29396763/

Kumar N, Sood S, Arora B, Singh M, Beena, Roy PS - "To Study the Effect of Vitamin D and E on Sodium-Fluoride-induced Toxicity in Reproductive Functions of Male Rabbits." Toxicol Int 19(2):182-7 (2012) doi: 10.4103/0971-6580.97220. PMID: 22778518; PMCID: PMC3388764
https://pubmed.ncbi.nlm.nih.gov/22778518

Yang D, Liu Y, Chu Y, Yang Q, Jiang W, Chen F, Li D, Qin M, Sun D, Yang Y, Gao Y - "Association between vitamin D receptor gene FokI polymorphism and skeletal fluorosis of the brick-tea type fluorosis: a cross sectional, case control study" BMJ Open 6(11):e011980 (2016) doi: 10.1136/bmjopen-2016-011980. PMID: 28170338; PMCID: PMC5129067.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129067/
Note: There are many studies involving fluoride and Vitamin D.

Gq/11

"The action of calcitriol on InsP(3) formation and Ca(2+) mobilization in Fura-2-loaded confluent osteoblasts involved Galpha(q/11)."

Le Mellay V, Lasmoles F, Lieberherr M - "Galpha(q/11) and gbetagamma proteins and membrane signaling of calcitriol and estradiol" J Cell Biochem. 75(1):138-46 (1999) doi: 10.1002/(sici)1097-4644(19991001)75:1<138::aid-jcb14>3.3.co;2-9. PMID: 10462712.
https://pubmed.ncbi.nlm.nih.gov/10462712/

Thyroid

"The present work shows a significant association between circulating 25(OH)D and HT".

Štefanić M, Tokić S - "Serum 25-hydoxyvitamin D concentrations in relation to Hashimoto's thyroiditis: a systematic review, meta-analysis and meta-regression of observational studies" Eur J Nutr 59(3):859-872 (2020) doi: 10.1007/s00394-019-01991-w. Epub 2019 May 14. PMID: 31089869
https://pubmed.ncbi.nlm.nih.gov/31089869/
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TSH

Postby admin » Sun Jun 28, 2020 1:59 am

Talaei A, Ghorbani F, Asemi Z - "The Effects of Vitamin D Supplementation on Thyroid Function in Hypothyroid Patients: A Randomized, Double-blind, Placebo-controlled Trial" Indian J Endocrinol Metab 22(5):584-588 (2018) doi: 10.4103/ijem.IJEM_603_17. PMID: 30294564; PMCID: PMC6166548
https://pubmed.ncbi.nlm.nih.gov/30294564/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166548/
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