A forum investigating the similarities between COVID-19 and fluoride poisoning, thyroid dysfunction and Gq/11 pathways.
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Selenium deficiency is associated with mortality risk from COVID-19, and disease severity (Moghaddam et al, 2020; Im et al., 2020).

It is also established that selenium deficiency and excess can worsen fluoride toxicity, as well as thyroid disorders. (The three deiodinases are selenoproteins).


Moghaddam A, Heller RA, Sun Q, Seelig J, Cherkezov A, Seibert L, Hackler J, Seemann P, Diegmann J, Pilz M, Bachmann M, Minich WB, Schomburg L - "Selenium Deficiency Is Associated with Mortality Risk from COVID-19" Nutrients 12(7):2098 (2020)

Im JH, Je YS, Baek J, Chung MH, Kwon HY, Lee JS - "Nutritional status of patients with COVID-19" Int J Infect Dis 100:390-393 (2020)


Chen J, Chen X, Yang K - "Effects of selenium and zinc on the DNA damage caused by fluoride in pallium neural cells of rats" J Hyg Res 29: 216-217 (200)

Guo XW, Lu CH, Bian JC - "Effects of fluoride and selenium on thyroid tissues and function in rats" Studies of Trace Elements and Health (4)(1998)[/i]

Hu AW, Liu XY, Qin YD - "Effect of fluorine on triiodothyronine and thyroxine in mice" Journal of Bengbu Medical College (4)(2008)


Andrade GRG, Gorgulho B, Lotufo PA, Bensenor IM, Marchioni DM - "Dietary Selenium Intake and Subclinical Hypothyroidism: A Cross-Sectional Analysis of the ELSA-Brasil Study" Nutrients 10(6):693 (2018)

Filipowicz D, Majewska K, Kalantarova A, Szczepanek-Parulska E, Ruchała M - "The rationale for selenium supplementation in patients with autoimmune thyroiditis, according to the current state of knowledge" Endokrynol Pol 72(2):153-162 (2021)


Beech SG, Walker SW, Arthur JR, Lee D, Beckett GJ - "Differential control of type-I iodothyronine deiodinase expression by the activation of the cyclic AMP and phosphoinositol signalling pathways in cultured human thyrocytes" J Mol Endocrinol 14(2):171-7 (1995)

Beech SG, Walker SW, Beckett GJ, Arthur JR, Nicol F, Lee D - "Effect of selenium depletion on thyroidal type-I iodothyronine deiodinase activity in isolated human thyrocytes and rat thyroid and liver" Analyst 120(3):827-31 (1995)
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