More on Fluoride & IQ

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More on Fluoride & IQ

Postby pfpcnews » Fri Dec 26, 2008 2:48 am

Liu M, Qian C - "Effect of endemic fluorosis on children's intelligence development: a Meta analysis" Zhongguo Dang Dai Er Ke Za Zhi 10(6):723-5 (2008)

Department of Health Statistics, China Medical University, Shenyang 110001, China.

OBJECTIVE: To investigate the effect of high levels of fluoride on children's
intelligence development by analyzing the literatures systematically.

METHODS: The literatures on the relationship between endemic fluorosis and children's intelligence development published between 1995 and 2007 were retrieved electronically and manually. A total of 13 relevant literatures that met the inclusion criteria were included for Meta analysis. Meta analysis was performed using the Coorporative network software RevMan 4.3.

RESULTS: The subjects of the 13 literatures included 2 508 children from the high fluoride group and 2 330 children from the control group. Meta analysis showed these literatures were inhomogenous (x2=268.05, p<0.01). Therefore a random effect model was used. The average effect scale (OR=-7.14; 95%CI: -9.90, -4.37) suggested a negative correlation between high fluorosis exposure and children's intelligence development.

CONCLUSIONS: Exposure to high levels of fluoride may adversely
influence children's intelligence development.
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