Effect of Cadmium and Fluorine on the Rat Dentition

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Ginn JT, Volker JF - "Effect of Cadmium and Fluorine on the Rat Dentition" Exp Biol Med (Maywood) 57(2):189-191 (1944)
From the University of Rochester School of Medicine and Dentistry,
http://ebm.sagepub.com/content/57/2/189.short

Summary

The ability of cadmium to diminish the degree of pigmentation of rat incisor enamel and to effect a reduction in blood hemoglobin has been confirmed. The ability of fluorine to bring about a comparable reduction in blood hemoglobin has also been observed. It is suggested that the pigmentary changes in the enamel and the fall in hemoglobin that results in the ingestion of both cadmium and fluorine is related to the ability of these elements to interact with iron-containing proteins. Unlike fluorine, cadmium in the concentration studied is ineffective in reducing experimental rat caries.