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河南省淮河流域深水井高碘高氟流行状况调查
作 者:侯国强 孙宁 李小烽 原春生 陈玕

作者机构:河南省疾病预防控制中心地方病预防控制所

出 版 物:《中国地方病防治杂志》 (Chinese Journal of Control of Endemic Diseases)

年 卷 期:2021年第36卷第1期

页 面:30-31

学科分类:10[医学] 1002[医学-临床医学]

主  题:淮河流域 水碘 水氟

摘 要:目的通过对淮河流域中下游地区的深水井水氟水碘含量及7-10岁儿童甲状腺肿大和8-12岁儿童氟斑牙患病率调查,研究该地区黄河故道区深水井氟、碘分布及危害。方法现场采集132眼集中供水工程深井末梢水样132份,每份样品分别测定水氟、水碘含量;抽查沈丘及郸城7-12岁儿童,采用触诊法检查甲状腺肿大情况,Dean氏法检查氟斑牙患病情况。结果调查沈丘、项城、郸城、鹿邑、淮阳、商水六县区132处集中供水的深水井,48处水氟小于1.0 mg/L,占36.36%;1.1-2.0 mg/L,44处,占33.33%;2.1-4.0 mg/L,40处,占30.30%。水碘10-100μg/L,39处,占29.54%;100-300μg/L,87处,占65.91%;300μg/L以上6处,占4.54%。沈丘7-10岁儿童43人,甲状腺肿大率2.32%,8-12岁儿童88人,氟斑牙患病率63.64%;郸城吴台7-10岁78人,儿童甲状腺肿大率2.56%,8-12岁儿童102人,氟斑牙患病率28.43%;郸城李楼7-10岁儿童125人,甲状腺肿大率0.80%,8-12岁儿童氟斑牙患病率25.50%。同一水样水氟水碘含量相关性r=0.83,P0.05。结论同一水样水氟、水碘测定结果分析发现,该区域集中供水水氟超标(1.0 mg/L)率达63.64%,使得原本处于点状或岛状分布的氟中毒病区变成了连片的大面积水氟超标区;水碘超过100μg/L的比例达到70.46%,氟碘含量呈高度相关性。结果提示在黄河故道的淮河流域中下游地区深井集中供水防治饮水型地方性氟中毒效果较差,同时,该区域应采取饮用水降碘措施。

Hou Guoqiang, Sun Ning, Li Xiaofeng, Yuan Chunsheng, Chen Gan - "Survey on the prevalence of high iodine and high fluoride in deep-water wells in the Huaihe River Basin of Henan Province" Chinese Journal of Endemic Disease Control 36(1):30-31 (2021)

Abstract:

The aim of this study is to investigate the fluoride and iodine content in deep well water in the lower reaches of the Huaihe River basin, as well as the prevalence of thyroid enlargement in 7-10-year-old children and the incidence of dental fluorosis in 8-12-year-old children. The study explores the distribution and hazards of fluoride and iodine in the Yellow River abandoned channel area of this region. The method involved collecting 132 samples of terminal water from the concentrated water supply project's deep wells on-site, and each sample was tested for fluoride and iodine content. Additionally, a sample survey was conducted on 7-12-year-old children in Shenqiu and Dancheng. Thyroid enlargement was examined using the palpation method, and dental fluorosis was assessed using the Dean method. The results revealed that among 132 deep wells in six counties (Shenqiu, Xiangcheng, Dancheng, Luyi, Huaiyang, and Shangshui), 48 wells had fluoride levels below 1.0 mg/L (36.36%), 44 wells had levels between 1.1-2.0 mg/L (33.33%), and 40 wells had levels between 2.1-4.0 mg/L (30.30%). Iodine levels ranged from 10-100μg/L in 39 wells (29.54%), 100-300μg/L in 87 wells (65.91%), and above 300μg/L in 6 wells (4.54%). In Shenqiu, among 43 children aged 7-10, the rate of thyroid enlargement was 2.32%, and among 88 children aged 8-12, the incidence of dental fluorosis was 63.64%. In Dancheng Wutai, among 78 children aged 7-10, the rate of thyroid enlargement was 2.56%, and among 102 children aged 8-12, the incidence of dental fluorosis was 28.43%. In Dancheng Lilou, among 125 children aged 7-10, the rate of thyroid enlargement was 0.80%, and among 8-12-year-olds, the incidence of dental fluorosis was 25.50%. There was a significant correlation between the fluoride and iodine content in the same water sample (r=0.83, P<0.05). In conclusion, the analysis of fluoride and iodine levels in the same water sample revealed that the rate of fluoride exceeding the standard (1.0 mg/L) in the concentrated water supply in this region was 63.64%, turning the originally scattered or island-like fluorosis areas into large continuous areas with excessive fluoride. The proportion of iodine in water exceeding 100μg/L reached 70.46%, and there was a high correlation between fluoride and iodine content. The results suggest that the effect of controlling drinking-type regional fluoride poisoning in the concentrated water supply of deep wells in the lower reaches of the Huaihe River basin, Yellow River abandoned channel, is not ideal. Simultaneously, measures should be taken to reduce iodine in drinking water in this region.

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河南省2020年饮水型氟中毒病区27个农村饮水安全工程水氟和水碘检测结果分析
作 者:陈玕 闫英洁 孙宁 张莉 郑合明 朱琳

作者机构:河南省疾病预防控制中心地方病预防控制所

出 版 物:《中国地方病防治杂志》 (Chinese Journal of Control of Endemic Diseases)

年 卷 期:2020年第35卷第5期

页 面:570-571

学科分类:10[医学] 1002[医学-临床医学]

基  金:河南省二〇一七年科技发展计划(172102310092)

主  题:饮用水安全工程 农村 氟含量 碘含量

摘 要:目的了解河南省地方性饮水型氟中毒病区农村饮水安全工程现状,为政府有关部门制定地方病防治规划和改水工程监测提供科学依据。方法采集河南省地方性饮水型氟中毒病区的27个农村饮水安全工程水样,测定其水氟和水碘含量。结果 27个工程水氟含量平均值为1.36 mg/L,水氟值0.5 mg/L、0.5~1.0 mg/L、1.1~1.2 mg/L、≥1.2 mg/L的工程分别占11.1%(3/27)、25.9%(7/27)、3.7%(1/27)和59.3%(16/27)。27个工程水碘含量中位数为67.9μg/L,水碘值10.0μg/L、10.0~50.0μg/L、50.1~100.0μg/L、100.1~300.0μg/L、≥300μg/L的工程分别占14.8%(4/27)、22.2%(6/27)、25.9%(7/27)、33.3%(9/27)和3.7%(1/27)。结论河南省地方性饮水型氟中毒病区27个农村饮水安全工程存在水氟水碘含量超标情况,建议加强水质监测,因地制宜地制定降氟降碘改水措施

Henan Province in 2020 drinking water fluorosis disease area 27 rural drinking water safety of water fluoridation and water iodine test results analysis

Chinese Journal of Endemic Disease Control 35(5):570-571 (2020)
Chen Gan Yan Yingjie Sun Ning Zhang Li Zheng Heming Lin ZHU Henan Province Disease Prevention Control Center endemic disease prevention control of the
ISSN: 1001-1889
Objective To understand the current status of rural drinking water safety projects in endemic drinking water fluorosis areas in Henan Province, and to provide scientific basis for relevant government departments to formulate endemic disease prevention and control plans and water improvement project monitoring. Methods The water samples of 27 rural drinking water safety projects in endemic drinking water fluorosis areas in Henan Province were collected to determine their water fluoride and water iodine content. Results The average water fluoride content of the 27 projects was 1.36 mg/L, and the water fluoride value of the 27 rural drinking water safety projects in Henan endemic drinking water fluorosis areas had excessive water fluoride and water iodine content. It is recommended to strengthen water quality monitoring and adapt to local conditions. Formulate measures to reduce fluoride and iodine to improve water.
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饮用水高氟碘对8~10岁儿童血清免疫物质水平的影响
作 者:侯国强 陈玕 孙宁 张莉 刘洋 原春生 杨金 郑合明 郝宗宇

作者机构:河南省疾病预防控制中心地方病预防控制所

出 版 物:《当代医学》 (Contemporary Medicine)

年 卷 期:2016年第22卷第30期

页 面:3-4

学科分类:10[医学] 1002[医学-临床医学] 100202[医学-儿科学]

基  金:河南省科技厅攻关课题(142102310390) 河南省科协指导课题(KX10J13)

主  题:水氟 水碘 白细胞介素21 血清IgG 血清IgM

摘 要:目的研究自然条件下,饮水高氟、碘对8~10岁儿童血清白细胞介素21(IL-21)水平及IgM、IgG含量的影响。方法选择饮水氟2.0 mg/L、碘中位数150 mg/L自然村8~10岁儿童90名为研究组,饮水氟1.0 mg/L、碘中位数50~80 mg/L自然村8~10岁儿童90名为对照组,检测其血液中IL-21水平及IgM、IgG含量。结果研究组儿童IL-21测定结果范围为432.4~7 790.9 pg/m L,中位数为912.01 pg/m L,对照组测定结果范围为302.3~4 324.8 pg/m L,中位数为588.84 pg/m L,二者差异有统计学意义(P0.01);研究组IgM含量1.11~4.02 mg/m L,对照组0.78~3.54 mg/m L,二者差异无统计学意义;研究组IgG含量8.81~19.98 mg/m L,中位数为13.34 mg/m L,对照组7.14~20.46 mg/m L,中位数为12.53 mg/m L,二者差异有统计学意义(P0.05)。结论自然状态条件下,饮水高氟、碘时8~10岁儿童IL-21水平明显升高,从而抑制自体免疫水平,致使血清IgG含量明显降低,但对IgM含量尚无明显影响,提示饮水高氟碘将导致8~10岁儿童自体免疫水平降低。
Effect of high fluoride and iodine in drinking water on serum immune substance levels in children aged 8-10

Contemporary medicine 2016, Issue 30, Volume 22, Page 3-4
author: Hou Guoqiang Chen Gan Sun Ning Zhang Li Liu Yang Yuan Chunsheng Yang Jin Zheng Heming Hao Zongyu
Henan Province Disease Prevention Control Center endemic disease prevention control of the
ISSN: 1009-4393
Objective To study the effects of high levels of fluoride and iodine in drinking water on the levels of serum interleukin 21 (IL-21) and the levels of IgM and IgG in children aged 8-10 under natural conditions. Methods Select drinking water fluoride>2.0 mg/L, median iodine>150 mg/L in natural villages with 90 children aged 8-10 years as the study group, drinking water fluoride <1.0 mg/L, median iodine 50-80 mg/L in natural villages Ninety children aged 8-10 years were a control group, and their blood levels of IL-21 and IgM and IgG levels were detected. Results The measurement results of IL-21 in children in the study group ranged from 432.4 to 7 790.9 pg/m L, with a median of 912.01 pg/m L, and the control group measured results range from 302.3 to 4 324.8 pg/m L, with a median of 588.84. pg/ml, the difference between the two was statistically significant (P<0.01); the IgM content of the study group was 1.11-4.02 mg/ml, and the control group was 0.78-3.54 mg/ml, the difference between the two was not statistically significant; the study group The IgG content was 8.81-19.98 mg/ml, the median was 13.34 mg/ml, the control group was 7.14-20.46 mg/ml, and the median was 12.53 mg/ml, the difference between the two was statistically significant (P< 0.05). Conclusion Under natural conditions, when drinking water with high fluoride and iodine, the level of IL-21 in children aged 8 to 10 years is significantly increased, thereby inhibiting the level of autoimmunity, resulting in a significant decrease in serum IgG content, but there is no significant effect on IgM content, indicating that drinking water is high Fluoride and iodine will reduce the level of autoimmunity in children aged 8 to 10 years.
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