2008 Urinary Fluoride of Workers Exposed to Organic Fluorine

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2008 Urinary Fluoride of Workers Exposed to Organic Fluorine

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有机氟作业工人尿氟检测结果分析
引用本文: 廖青,阴旅宁,刘兆霖,梅玉琴,孙建忠.有机氟作业工人尿氟检测结果分析[J].职业卫生与病伤,2008,23(2):71-72.
作者姓名: 廖青 阴旅宁 刘兆霖 梅玉琴 孙建忠
作者单位: 1. 自贡市疾病预防控制中心,四川,自贡643000
2. 中昊晨光化工研究院
摘 要: 目的了解有机氟作业工人尿氟含量水平。方法采集某企业7个车间接触有机氟(二氟一氯甲烷、三氟氯乙烯、四氯乙烯、八氟异丁烯)工人656名,以及该企业从未接触过有机氟作业的电工、管理、后勤人员255名的晨尿,按WS/T30-1996,吸取10.0ml尿液于50ml塑料烧杯中,加入总离子强度缓冲液10.0ml,用PXJ-IC^+型离子活度计,氟离子选择电极法测定。用t检验、F检验和百分位数程序对数据进行统计学处理分析。结果656名有机氟作业工人尿氟含量为0.10~4.74mg/L,均值1.08mg/L,255名对照组工人尿氟含量为0.16~2.95mg/L,均值0.90mg/L,作业组尿氟含量均值明显高于对照组,差异有统计学意义(P〈0.01)。对照组尿氟含量呈偏态分布,尿氟百分位数(P2.5~P97.5)为0.23~2.27mg/L,建议本地区尿氟正常值上限为2.3mg/L。作业组男性尿氟均值水平高于女性(P〈0.01);作业组尿氟含量与年龄、接触工龄差异无统计学意义,F=2.32,P〉0.05,但有随工龄增长,尿氟均值增加的趋势。结论有机氟作业组与对照组的尿氟含量有显著差别,作业组工人尿氟含量与性别有关,与年龄无关,与接触工龄关系不显著;本地区尿氟正常值上限为2.3mg/L。

关 键 词: 有机氟 作业工人 尿氟
文章编号: 1006-172X(2008)02-071-02
修稿时间: 2008年1月20日

Urinary Fluoride of Workers Exposed to Organic Fluorine

Affiliation: LIAO Qing, YIN Li-ning, LIU Zhao-lin, et al.( Center for Disease Control and Prevention of Zigong City, Zigong 643000, Sichuan Province, China)

Abstract: Objective To find out the urine fluoride concentration levels in workers exposed to organic fluorine. Methods The urinary fluoride was detected by PXJ-IC^+ ion-meter and fluoride ion by electrode methed. Results The urine fluoride concentrations in control group showed skew distribution. The percentile of urinary fluoride concentrations (P2.5 - P97. 5 ) in control group was 0. 23 to 2.27 mg/L. The mean urine fluoride concentration of 656 workers exposed to fluorine ( 1.08 mg/L) was significantly higher than those of the control (0. 90 mg/L) (P 〈0. 01 ). The mean urine fluoride concentration of male was higher than that of female(P 〈 0. 01 ). There was no significant relationship between urine fluoride concentrations and age or length of service, but it seemed that the urine fluoride concentrations figured on a rising trend along with the increase in length of service. Conclusion There were significant differences in the urine fluoride concentration between workers exposed to organic fluorine and the control. There was correlation between the urine fluoride concentration of workers exposed to organic fluorine in sexes, but no significant correlation in age and length of service. The authors suggested that the upper limit of normal range for urine fluoride concentration was 2. 3 mg/L.

http://www.alljournals.cn/view_abstract ... rom_type=1
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Determination of urine ALP activity in workers exposed to organic fluorine
Cite this article: Xu Zhaofa,Guan Jingkun,Lin Xinfang,Li Gexin,Zhang Zhiyou.Determination of ALP Activity in Urine of Workers Exposed to Organic Fluorine[J].Chinese Journal of Industrial Medicine,1990(3).
author name: Xu Zhaofa Guan Jingkun Lin Xinfang Li Gexin Zhang Zhiyou
Author unit: China Medical University (Xu Zhaofa, Guan Jingkun, Lin Xinfang, Li Gexin), Fuxin Occupational Defense Institute (Zhang Zhiyou)
Summary: The urine ALP activity of 183 workers exposed to organic fluorine was measured, and the results showed that the urine ALP activity of workers exposed to organic fluorine for a long time was significantly higher than that of the control group without fluorine exposure. The urinary ASP activity of female workers was significantly higher than that of men, and there were differences in urinary ALP activity between different types of work. The urinary ALP activity of workers in polymerization and pipe pushing was higher than that in monomer. However, there was no significant difference in urinary ALP activity at different ages and working years. The results suggest that long-term exposure to organic fluorine can cause certain damage to workers’ kidneys.

Key words: Organic fluorine ALP kidney damage

Determination of ALP Activitity in Urine of Workers Exposed to Organic Fluoride
Xu Zhaofa.Determination of ALP Activitity in Urine of Workers Exposed to Organic Fluoride[J].Chinese Journal of Industrial Medicine,1990(3).
Authors: Xu Zhaofa
Abstract: The alkaline phosphatase (ALP) activities in urine in 183 workers exposed to organicfluoride were detemined. The results showed that the urinary ALP activities in workers exposed to organic fluoride for 1 to more than20 years were significantly higher than theseof non-exposed control group. The urinaryALP activities in female workers were signifi-cantly higher than that of male workers. Sig-nificant differences in ALP activities were fo-und among different types of work. The ALPactivities in urine showed no change among the different ages or the different periods of service. The results indicated that the long-term exposure to organic fluoride might cause kidney damage of the workers.
Keywords: organic fluoride uirnary ALP kidney damage

http://www.alljournals.cn/view_abstract ... rom_type=1
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