Studies on the effects of fluoride on "insulin":
© 2007 - 2013 PFPC
1. 谢永平, 葛相金, 姜玉亭, 逄明英, 范迎熙, 王孚伦, 魏增福, 赵贵禄, 秦爱琼. 高氟对人体胰岛B细胞功能影响的研究. 中国地方病学杂志 CHINESE JOURNAL OF ENDEMIOLOGY
2000 Vol.19 No.2 P.84-86
Clinical study of effect of high fluoride on the function of the pancreatic islet's B cells
Objective: Study the effect of excessive fluoride intaken on the function of the pancreatic islet's B cells.
Methods: Perform x-ray,determinate the ［F］ in the urine,make OGTT insulin and C-peptide releasing test in the serum,and analyse the drinking water quality of the exposed group and the control group.
Results: ①The ［F］ in drinking water and the geometrical mean of the ［F］ in the urine of the people of the exposed group were higher than those of the control group.②The fasting blood glucose concentration and the peak value after oral glucose in the exposed group were higher than those of the control group.The peak value was found later in the exposed group than those in the control group.③The detectable rate of Diabetes and IGT in the exposed group was higher than that in the control group.④The blood-insulin and the C-peptide in the exposed group were lower than those in the control group.While the peak value after oral glucose was found later in the exposed group were lower than in the control group.Conclusions Excessive fluoride can do much harm to the function of the pancreatic islet's B cells and the effects would change with the degree of fluorosis.
1 post • Page 1 of 1