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1991 - High F-/Low I Environment and Subclinical Cretinism

 
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PostPosted: Sat Aug 17, 2013 3:13 am    Post subject: 1991 - High F-/Low I Environment and Subclinical Cretinism Reply with quote

2. 林法福,艾海提,赵洪新.新疆高氟低碘环境与亚临床型克汀病[J].地方病通报,1991,6(2):62-67
http://dfbt.chinajournal.net.cn/EditorBN/WebPublication/paperDigest.aspx?paperID=DFBT199102016&isCnki=ck01
FULL TEXT:
http://www.docin.com/p-102217969.html

本文对和田不同类型的碘缺乏病区,采用瑞文联合型中国农村智力常模表,分别随机抽样检查了7~14岁学生130名,并同步检查了听力、四项精神运动及甲状腺功能。高氟低碘病区儿童平均IQ71.096.84,平均听阈24.0813.18dB,骨龄发育落后检出率28.5%,24小时甲状腺吸I~(131)率59.8714.63%,TSH 21.099.43μU/ml,亚克汀病患病率15.71%;低碘病区平均IQ 77.3211.54,平均听阈19.917.23 dB,骨龄发育落后检出率13.5%,甲状腺吸I~(131)率50.2619.25%,TSH 11.0511.49μU/ml,亚克汀病患病率9.36%。补碘对照区平均IQ 95.7617.52,平均听阈16.083.21 dB,骨龄发育落后检出率3.88%,甲状腺吸I~(131)率23.6111.71%,TSH6.262.88μU/mL,亚克汀病患病率为3.20%。上述各项参数和病区之间,均有显著差异。说明在缺碘病区同时并存高氟摄入时,氟可加剧由缺碘而引起的中枢神经损害和体躯发育障碍。在104例精神轻度发育迟泄的儿童中,亚克汀病的检出率69.23%。
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