1998 - Effects of fluoride and selenium on rat thyroid

1998 - Effects of fluoride and selenium on rat thyroid

Postby admin » Fri Sep 13, 2013 1:25 am

144. 卢传华,郭晓尉,边建朝,叶平,咸树梅,刘源,纪庆宪;高氟与补硒对大鼠甲状腺影响的实验研究[J];中国地方病学杂志;1998年02期
http://lib.cnki.net/cjfd/ZDFB802.018.html
http://www.cqvip.com/QK/90421X/199802/5178800.html
Zhuan et al. - "Effects of fluoride and selenium on the thyroid gland of rats" Chinese Journal of Medicine (2) (1998)

观察了饮用高氟水及加硒大鼠的甲状腺组织结构和甲状腺激素变化。结果表明,早期甲状腺滤泡上皮细胞增生活跃、游离甲状腺激素水平显著升高;后期甲状腺滤泡上皮细胞出现退行性变,FT3和T4水平明显降低;补硒与甲状腺激素水平有一定关系。提示高氟在早期使甲状腺兴奋,甲功高度代偿,后期则抑制甲状腺使甲功低下;氟与甲状腺组织及功能的改变与摄氟时间密切相关。
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