1989 - Effects of F- on thyroid - experimental study

1989 - Effects of F- on thyroid - experimental study

Postby admin » Thu Feb 06, 2014 9:06 am

59. 董仲,刘万兴,刘家骝.慢性氟中毒对甲状腺影响的实验研究.中华病理学杂志,1989,18(3)226~227
http://lib.cnki.net/cpfd/EGYN198507001056.html
Yu Y et al - "Experimental study of chronic fluoride poisoning effects on the thyroid gland" Journal of Pathology 18(3):226-227 (1989)

正慢性氟中毒对甲状腺影响的问题仍然是一个争论较为激烈,尚未定论的问题。有资料表明过量的氟在甲状腺中蓄积,可以影响甲状腺滤泡上皮细胞摄取和浓集碘及甲状腺激素的合成和分泌,引起血清T3、T4降低,TSH升高,致甲状腺肿的发生。但与之截然相反的资料却认为过量的氟对甲状腺无影响。为此,作者检查了氟骨症患者血清T3、T4、TSH水平,并进一步研究了慢性氟中毒大鼠甲状腺功能及其结构变化,企图深入探讨慢性氟中毒甲状腺的变化及其机制。
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