2013 - Effects of High F and I on DF and Goiter 8-10 yr olds

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2013 - Effects of High F and I on DF and Goiter 8-10 yr olds

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170. 作 者 刘洋, 陈玕, 侯国强, 余波, 郑合明, 郝宗宇; 中心);饮水中高碘高氟对8~10岁儿童甲状腺肿与氟斑牙流行影响研究
当代医学 2013年01期 1-3页
http://new.med.wanfangdata.com.cn/Paper ... x201301002
http://www.alljournals.cn/view_abstract ... 08D58E97FA
10.3969/j.issn.1009-4393.2013.1.001
Liu Yang et al. - "Research on the impact of fluoride and iodine in drinking water for 8-10 year-old children - prevalence of goiter and dental fluorosis." Contemporary Medicine (01)1-3 (2013)

目的探讨高碘高氟对儿童甲状腺肿与氟斑牙的影响及特点.方法对黄泛区水源性高碘高氟和高氟适碘区(研究组)、低氟适碘区(对照组)全部8~10岁儿童共3053名进行甲状腺肿、氟斑牙检测.结果甲状腺肿检出率:高碘高氟组(15.41%)高于高氟适碘组(10.02%),χ2=14.678,P<0.01).两组均高于适碘低氟组(5.19%),分别为χ2=48.729,P<0.01;χ2=15.599,P<0.01.氟斑牙检出率:研究组间高碘高氟组(52.84%)与高氟适碘组(49.05%)无差异,χ2=3.155,P>0.05,但均高于对照组(5.68%),分别为χ2=463.237,P<0.01;χ2=432.845,P<0.01.结论高氟高碘对甲状腺肿的发生具有叠加、协同效应;对氟斑牙的形成,高碘与高氟无叠加协同效应.

Objective To investigate the effect and characteristics of high iodine and high fluoride on goiter and dental fluorosis in children. Methods A total of 3053 children aged 8 to 10 years old in the water-derived high iodine and high fluoride and high fluoride suitable iodine area (study group) and low fluoride suitable iodine area (control group) were examined for goiter and dental fluorosis. Results The detection rate of goiter: the high iodine and high fluoride group (15.41%) was higher than the high fluoride and suitable iodine group (10.02%), 2=14.678, P<0.01). The two groups were higher than the appropriate iodine and low fluoride group (5.19%), respectively 2=48.729, P<0.01; 2=15.599, P<0.01. Dental fluorosis detection rate: There was no difference between the study groups between the high iodine and high fluoride group (52.84%) and the high fluoride and appropriate iodine group (49.05%), 2=3.155, P>0.05, but both were higher than the control group (5.68%) , respectively, 2=463.237, P<0.01; 2=432.845, P<0.01. Conclusion High fluoride and high iodine have additive and synergistic effects on the occurrence of goiter; on the formation of dental fluorosis, high iodine and high fluoride have no additive synergistic effect.
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