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1998 - Effects of fluoride/selenium on rat thyroid function

Posted: Fri Sep 13, 2013 1:28 am
by admin
143. 郭晓尉,卢传华,边建朝;氟硒对大鼠甲状腺组织及功能的影响[J];微量元素与健康研究;1998年04期


Re: 1998 - Effects of fluoride/selenium on rat thyroid funct

Posted: Tue Jun 23, 2020 11:02 pm
by admin
【Abstract】: The changes of thyroid tissue and thyroid hormones in rats drinking high-fluorine water and selenium were observed. The results showed that the proliferation of thyroid follicular epithelial cells was active early, and the level of free thyroid hormone was significantly increased. In the later stage, thyroid follicular epithelial cells showed degenerative changes, and the levels of FT3 and T4 were significantly reduced. Selenium supplementation has a certain relationship with thyroid hormone levels. It is suggested that high fluoride excites the thyroid gland in the early stage, and the nail function is highly compensated. In the later stage, it inhibits the thyroid gland to make the nail function lower. Fluorine changes in thyroid tissue and function are closely related to the time of fluoride ingestion.

NOTE: First increase - then decrease. (Just like TSH)