2001 - FX of F- on I metabolism in chicken

2001 - FX of F- on I metabolism in chicken

Postby admin » Tue Jan 05, 2016 4:31 am

27. 康世良,刘国艳,柴春彦.氟对鸡甲状腺中碘代谢的影响[J].动物医学进展,2001,22(3):7~72
Kang Shiliang, Liuguo Yan, Chai Chunyan - "Fluoride effect on thyroid iodine metabolism in chickens" Progress in Veterinary Medicine 22 (3):7-72 (2001)
http://www.alljournals.cn/view_abstract ... rom_type=1

为探讨氟对鸡甲状腺中碘代谢的影响,选用250只1日龄蛋鸡,随机分为5组,每组50只,饲喂相同的全价日粮。第Ⅰ组:正常对照组,Ⅱ,Ⅲ,Ⅳ,Ⅴ组在日粮中添加不同水平的氟化钠,使日粮中氟的含量分别为500,1000,1500和2000mg/kg,试验期为150d,每隔30d采集血样,测定血清中氟含量、甲状腺中碘含量,观察试验鸡的临床表现。成功地复制出不同程度的鸡慢性氟中毒模型,试验鸡日粮含碘量正常。结果表明各中毒组甲状腺中碘含量在整个试验期内均不同程度地低于对照组,呈明显的剂量-效应和时间-效应关系。甲状腺中碘含量变化和相应时期的血清氟含量间呈显著的负相关(r=-0.814)。说明氟能明显地抑制甲状腺摄取和聚集碘的能力,干扰碘的正常代谢,进而影响整个甲状腺的结构和功能。

To investigate the influence of fluorine on the thyroid iodine metabolism in chicken, choice of 250 day-old laying hens were randomly divided into five groups, each 50, were fed the same complete diet. Group Ⅰ: normal control group, Ⅱ, Ⅲ, Ⅳ, Ⅴ group added to the diet of different levels of sodium fluoride, the content of dietary fluoride were 500,1000,1500 and 2000mg / kg, the test period 150d, blood samples were collected every 30d, the fluorine content in serum thyroid iodine content, clinical trials show chickens. Successfully copied varying degrees of chickens with chronic fluorosis model, test the iodine content of normal chicken diets. The results showed that each poisoned group thyroid iodine content throughout the test period are different degrees lower than the control group, showed significant dose - effect and time - effect relationship. Fluoride content between serum thyroid iodine content and the corresponding period of the change was a significant negative correlation (r = -0.814). Description fluorine can significantly inhibit the ability of thyroid iodine uptake and accumulation, and interfere with the normal metabolism of iodine, which in turn affect the structure and function of the entire thyroid.
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